As the key to decarbonization development in the field of transportation, new energy vehicles have their charging demand replenishment affected by the layout planning of basic charging facilities. To address this problem, a regional electric-hydrogen generation and charging station（EHGCS）planning study based on electric-hydrogen-road-vehicle synergy is proposed. Firstly, a time-flow model is established to analyze the topology of traffic roads, and Dijkstra is used to simulate the driving paths of new energy vehicles, so as to establish an electric-hydrogen demand prediction model for new energy vehicles considering the vehicle-road-network coupling. secondly, the whole process of producing, compressing and storing hydrogen is analyzed, and the operation architecture and energy flow model of the EHGCS are constructed. Thirdly, the planning model of the regional electric-hydrogen charging station is established with the goal of minimizing the economic costs, such as investment, operation, network loss, etc., taking into account the constraints of road-network coupling, distribution network and safe operation of equipment, and solving for the optimal planning scheme by using the second-order conical relaxation technique；finally, some arterial roads of urban areas of a certain city and the nodes of the distribution network of IEEE33 are used as the examples to validate the validity and practicability of the proposed methodology.