With the rapid development of energy and information communication technology, the participation of novel demand resources in system operation and control has become an important part of grid operation. Due to the inherited differences and uncertainties of demand response, accurately quantifying the response performance of demand response resources has become the important tasks of grid operation. For this a demand response performance evaluation system is establisged from the perspective of power system operation and control, defines various indicators to assess the timeliness, accuracy, reliability and utilization of demand response and provides corresponding calculation methods. An example demand response case is used to demonstrate how to calculate the performance indicators quantitatively.Through comparison of the response performance indicators of three different responses, it is verified that the proposed quantitative evaluation indicators of response performance conform to the intuitive judgment of response performance and also provide more comprehensive evaluation information. The response performance indicators can accurately evaluate the response performance of novel demand response resources, and provide the basis for system operations, settlements and compliance.