With various energy types such as electricity, gas,heat and cold, the micro energy grid can realize the cascade utilization of energy and effectively promote the consumption of various new energy sources such as wind and solar. Compared with electric vehicles, hydrogen fuel cell vehicles have the advantages of short refueling time and strong endurance, and have been rapidly developed in recent years. An optimization scheduling method of micro energy grid with the penetration of hydrogen refueling station is proposed. Under the premise of meeting the energy demand of electricity, gas, heat and cold in this region, the optimal scheduling strategy for the hydrogen fueling station is formulated, which can effectively promote the development and utilization of hydrogen energy. Case studies compare the independent operation of the micro energy grid and the hydrogen refueling station. The cooperative operation of them verify the superiority and effectiveness of the proposed model and method.