An air conditioning control strategy with supplyand demand interaction is proposed under the background of virtual power generation. The indoor energy management device is used to predict the room temperature and calculate the load adjustable capacity controlled by the indoor energy management device. After each residential energy management device reports the adjustable capacity, the grid side issues load cutting instructions, and the residential energy management device accepts the instructions to centrally regulate the air conditioning load, providing a large amount of adjustable capacity for the grid side when maximum comfort of users is guaranteed. The virtual power plant technology is fully used and the physical energy management device is combined to realize the centralized control of largescale air conditioning load.