The demand-response business model with load aggregators as the middleman can fully exploit the potential of the demand-side resources and achieve the comprehensive optimization of power grid. Based on fuzzy set pair analysis, the potential evaluation method of demand response is proposed. By analyzing the influences of clients’response, the index system is established. Based on fuzzy set pair analysis, a model of potential assessment is established to achieve a preliminary quantification of user response potential. Through the load distribution simulation experiment between the aggregator and the user, the effectiveness of the evaluation method in improving the accuracy and task completion rate of the load reduction is verified.