Virtual power plants can aggregate adjustable load resources at the end of distribution network to participate in power system calls to alleviate the problems faced by the supply and demand balance. At the same time, the power regulation of the end resources affects the operation quality of the distribution network, and the invocation of load-side resources can reduce the peak-to-valley difference in the distribution network area and reduce the system network loss. To this end, a virtual power plant with the distribution network operator as the main body is constructed, and a multi-objective optimization model of distribution network virtual power plant based on AUGMECON2 is proposed, which invokes the end load resources of distribution network to participate in the demand response with the operation benefit,distribution network peak-valley difference and distribution network loss as the objective functions, and improves the operation quality of distribution network while improving the operation benefit. The Pareto frontier of the proposed multi-objective optimal problem is obtained by AUGMECON2, and a compromise solution is obtained by considering fairness. Finally, simulation analysis based on the modified IEEE 33-node distribution network system is conducted to verify the effectiveness of the proposed model.