Different utilization approaches in the integration and consumption of clean energy are taken as the research object,and an economic benefit evaluation index system for multi- agent demand response is constructed to participate in the integration and consumption of clean energy from the three main bodies of power users, power grid enterprises and power generation enterprises. The model evaluates economic benefits. The research results show that the economic benefit evaluation level of participating in the multi- energy complementary system consumption is excellent,the economic benefit evaluation level of participating in the microgrid and virtual power plant consumption is good, and the economic benefit evaluation level of participating in the wind and solar storage and consumption is unqualified. On the basis of considering the degree of evaluation grade bias, it is further found that the economic benefits of participating in the generation and consumption of virtual power plants are slightly higher than those of participating in the generation and consumption of microgrids. The research conclusions are helpful to optimize the integrated con sumption and utilization of different clean energy sources, and provide an effective decision-making basis for the establishment of utilization methods based on the results of economic benefit evaluation.