With the deepening of power market reform in the east of Mengdong region, the scale of power trading has been gradually expanded, and power settlement errors and deviation handling have been the focus and difficulty of power trading settlement in east of Mengdong. To address the above problems, a mathematical model of user electricity bill settlement based on the settlement rules of Mengdong electricity trading center is constrcted. Sensitivity analysis is conducted on the issue of the transmissibility of meter reading errors, the link to the transmission effect of meter reading error is determined. According to this impact link, two measures such as“early warning”and“spread income analysis”are proposed to deal with the deviation of bill settlement and profit loss caused by meter reading errors of customers, the effectiveness of the measures are verificated by simulation of arthmetic cases.