Rural industry is not only an important field for rural economic development and electrification, but also an important regional resource to interact with power grids through demand response. Different from large-scale industrial loads, rural industrial loads often require human assistance and have the characteristics of fixed and repeatable production processes. In order to exploit the adjustability of rural industrial loads, a load model considering rural production characteristics such as working hours and output requirements is established. For a more detailed description, the specific model is built based on the liquor-brewing industry. Based on this, a multi-scenario demand response strategies and operation optimization model are constructed for the rural distribution network to manage the demand response resources without affecting user production output. A case study is carried out to verify the proposed strategy based on the realistic load data of a 10 kV rural distribution network in Guizhou. The proposed strategy could exploit 36.1% of the example rural industry’s capacity for peak shaving without affecting user production output.