A multi-parameter economic analysis model is established and the influence degree of parameters is analyzed for optimal design of air conditioning terminal system. The results show that the proportion of operation and maintenance costs is not high,the difference in labor costs does not affect the trend of cost changes, but the duration of operation has a greater impact on operation costs. The longer the operation time, the greater the impact on the unit efficiency. Distributed terminal units with small air volume are economical and energy-saving, and the control strategy is flexible.The integral air conditioning unit has wide adaptability and is the optimal solution for the air conditioning terminal system of most terminals. For the complex situation of electricity price policy, specific problems should be analyzed in detail, and an accurate optimization plan should be obtained by substituting into the model. The research provides a reference for the optimal operation and design of the air-conditioning terminal system in traffic buildings.